Radiation-induced Esophagitis Market Insights, Epidemiology, and Market Forecast
DelveInsight's "Radiation-induced Esophagitis Market Insights, Epidemiology, and Market Forecast-2032" report delivers an in-depth understanding of the Radiation-induced Esophagitis, historical and forecasted epidemiology as well as the Radiation-induced Esophagitis market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.
The Radiation-induced Esophagitis market report provides current treatment practices, emerging drugs, Radiation-induced Esophagitis market share of the individual therapies, current and forecasted Radiation-induced Esophagitis market Size from 2019 to 2032 segmented by seven major markets. The Report also covers current Radiation-induced Esophagitis treatment practice/algorithm, market drivers, market barriers and unmet medical needs to curate the best of the opportunities and assesses the underlying potential of the Radiation-induced Esophagitis market.
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Radiation-induced Esophagitis: An Overview
Radiation-induced esophagitis is frequent and dose-limiting toxicity of thoracic radiotherapy (RT), especially when delivered concurrently with cytotoxic chemotherapy. Radiation esophagitis is inflammation, edema, erythema, and erosion of the mucosal surface of the esophagus caused by radiation therapy to nearby or related structures that cause cell damage, produce proinflammatory cytokines, and lead to the development of free-oxygen radical species related to radiation therapy.
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Radiation-induced Esophagitis Treatment Market
Radiation esophagitis is a common, dose-limiting, early adverse effect of radiation treatment of thoracic tumors. Its incidence is greater with higher radiation dose and concurrent chemotherapy. Early symptoms, usually following two to three weeks of treatment, include dysphagia and odynophagia. Topical anesthetics such as viscous lidocaine (Xylocaine), proton pump inhibitors, and promotility agents may provide symptomatic relief. Dietary modifications shown to reduce incidence and severity include a bland diet and avoidance of alcohol, coffee, and acidic foods.
Radiation-induced Esophagitis Market Insights
Radiation esophagitis is treated symptomatically. Pain is managed with topical analgesics such as liquid morphine sulfate. Combined solutions of equal parts viscous xylocaine, aluminum hydroxide–magnesium carbonate, and diphenhydramine are used. Since patients with esophagitis have decreased lower esophageal sphincter pressure, reflux is treated with proton-pump inhibitors and dietary modifications. Sodium bicarbonate's alkalotic properties can treat reflux and prevent Candida albicans superinfection. Strictures are managed with endoscopic dilation.
Radiation-induced Esophagitis Market Forecast
Amifostine, an organic triphosphate, has been studied and shown to act as a radioprotector. It is thought that this medication acts as an antioxidant to neutralize the free-oxygen radicals produced during ionizing radiation. A study performed to look at the effects of amifostine in patients with advanced non-small cell lung cancer showed improvement of swallowing dysfunction but no effect on reducing rates of esophagitis in severe cases.
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Radiation-induced Esophagitis Market Landscape and Emerging Drugs
The emerging drugs landscape does not represent a particularly promising picture due to the lack of later stage clinical products which is quite evident based on the scarcity of clinical trials being conducted for pivotal stage in 7 MM.
Radiation-induced Esophagitis Market Outlook
The Radiation-induced Esophagitis market outlook of the report helps to build a detailed comprehension of the historic, current, and forecasted Radiation-induced Esophagitis market trends by analyzing the impact of current Radiation-induced Esophagitis therapies on the market, unmet needs, drivers and barriers, and demand for better technology.
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Radiation-induced Esophagitis Market Report Scope
· The report covers the descriptive overview of Radiation-induced Esophagitis, explaining its causes, signs and symptoms, pathophysiology, diagnosis and currently available therapies
· Comprehensive insight has been provided into the Radiation-induced Esophagitis epidemiology and treatment in the 7MM
· Additionally, an all-inclusive account of both the current and emerging therapies for Radiation-induced Esophagitis is provided, along with the assessment of new therapies, which will have an impact on the current treatment landscape
· A detailed review of the Radiation-induced Esophagitis market; historical and forecasted is included in the report, covering drug outreach in the 7MM
· The report provides an edge while developing business strategies, by understanding trends shaping and driving the global Radiation-induced Esophagitis market
Radiation-induced Esophagitis Market Insights Report Highlights
· In the coming years, the Radiation-induced Esophagitis market is set to change due to the rising awareness of the disease, and incremental healthcare spending across the world; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market
· The companies and academics are working to assess challenges and seek opportunities that could influence Radiation-induced Esophagitis R&D. The therapies under development are focused on novel approaches to treat/improve the disease condition
· Major players are involved in developing therapies for Radiation-induced Esophagitis. The launch of emerging therapies will significantly impact the Radiation-induced Esophagitis market
· A better understanding of disease pathogenesis will also contribute to the development of novel therapeutics for Radiation-induced Esophagitis
· Our in-depth analysis of the pipeline assets across different stages of development (Phase III and Phase II), different emerging trends and comparative analysis of pipeline products with detailed clinical profiles, key cross-competition, launch date along with product development activities will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the research and development activities.
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